目的：復發性口腔潰瘍（Recurrent Oral Ulceration, ROU）是口腔黏膜或上皮反覆破損腫痛，其週期性發作及潰瘍疼痛等症狀導致生活質量下降，而中醫理論的陰虛火旺是ROU的重要誘因。因此本研究的目的是探討應用蜂蜜性涼味甘的特質和針對陰虛體質的飲食調理對ROU的療效，為ROU患者和臨床護理提供此另類療法的借鑒，以有效降低及預防ROU發作。方法：以網上問卷形式配合「中醫體質分類與判定」量表，評估及篩選具有陰虛體質的ROU參與者，以飲用蜂蜜合併飲食衛教，以及在口腔潰瘍發生時，蜂蜜外敷創面等措施，進行口腔潰瘍改善計劃，並在干預中期及後期進行成效評估。結果：8名符合納入標準的參與者過往口腔潰瘍發作頻率每月平均1.5次，每次發作天數平均4.6天。經過8週干預後5位參與者在過程中無發生口腔潰瘍。干預後口腔潰瘍疼痛評分平均降低約3分，而陰虛體質評分平均下降36.5分。結論：利用蜂蜜的甘寒性質合併飲食衛教對ROU能夠有效縮短病程、減輕症狀和預防作用，但對陰虛體質改善效果不明顯。

Objective: Recurrent Oral Ulcreation (ROU) are the repeated damage and swelling of the oral mucosa or epithelium, and their periodic episodes and symptoms such as pain leads to a decrease in quality of life. The yin deficiency with effulgent fire in traditional Chinese medicine theory is an important trigger for ROU. Therefore, the purpose of this study is to explore the effect of honey, which is cool and sweet, and diet education for yin-deficiency constitution, on ROU, so as to provide a reference for ROU patients and clinical nursing to effectively reduce and prevent ROU. Methods: In the form of an online questionnaire in conjunction with the "Classification and Determination of TCM Constitution" scale, the ROU participants with yin deficiency constitution were evaluated and screened, and measures such as drinking honey combined with dietary health education, as well as external application of honey when mouth Ulcreation occurred to carry out oral ulcer improvement plans, and to evaluate the effectiveness in the middle and late stages of the intervention. Results: Eight participants who met the inclusion criteria did not develop mouth Ulcreation at the beginning of the intervention, compared with the average frequency of mouth ulcer attacks in the past 1.5 per month, with an average of 4.6 days per episode. After 8 weeks of intervention, 5 participants did not have mouth Ulcreation in the process, while the other 3 participants had oral ulcer attacks in the process, and 1 participant had a frequency of 2, 1 and 2 attacks per month before, during and after the intervention, with an attack duration of 7, 5 and 4 days/ time; There were also 1 participant for 3, 1, 1 time/month and 6, 5, 4 days/time; The other participants had 1, 1, and 0 episodes, and the duration of the attack was maintained for 5 days. The oral ulcer pain score decreased by about 3 points on average after the intervention, while the yin deficiency constitution score decreased from 54.1 points before the intervention to 47.6 points after the intervention. Conclusions: Except for one participant who had poor results due to honey use, personal stress factors and family eating habits, the remaining seven participants all had positive improvements in various evaluations. The results showed that the use of honey's sweet and cold nature combined with diet and health education could effectively shorten the course of the disease, reduce symptoms and prevent ROU, but the effect on improving the yin deficiency constitution was not obvious.